If you're a big fan of House M.D., the TV show, you'd know Thirteen, who's suffering from Huntington's disease or Huntington Chorea. Thirteen, a bisexual, is portrayed by Olivia Wilde.
Huntington's disease is a genetic disorder characterized by progressive muscle rigidity and dementia accompanied by chorea (abnormal involuntary movement disorder) and often seizure.
The onset of the disease is by age 40 and (may be) in childhood.
And death occurs in 5 to 15 years.
Related topic: Human Diseases (Parkinson's disease)